Partner Fund Management (PFM) generally uses bottom-up analysis to identify trends, investment themes and core investment opportunities across asset classes and geographies in a wide range of investment instruments. The firm may invest in various industries or sectors, including, but not limited to, communications and media, consumer, energy, financials, healthcare, industrials, materials, technology and utilities. Their main investment strategies include diversified global and healthcare. PFM seeks to identify out- and under-performing companies that have the widest expectation gaps relative to consensus. In some cases, they may apply a catalyst-driven investment approach to express their fundamental view with respect to a company. PFM may also engage in top-down macro-economic analysis to identify opportunities, whether on a directional or relative value basis, across a wide range of global markets and investment instruments. They may consider economic, political and financial market conditions in seeking to identify attractive investment opportunities. The firm invests in and trades a wide range of investment instruments, including securities, options, ETFs, futures, currencies, derivatives, debt instruments and other assets that are financial instruments. They take both long and short positions in such investment instruments.