Stonepine Capital Management focuses primarily, but not exclusively, on equity and equity-related securities in US publicly healthcare companies. The firm seeks to invest in companies whose valuations reflect a material discount to their fundamental value in the healthcare space. Stonepine typically prefers to invest in companies at a price reflecting a discount to current commercial and financial assets alone.The Stonepine Funds' investment objective is to achieve superior absolute returns while preserving capital. They have formed Special Purpose Vehicles (SPVs) whose investment objective may differ because these investments tend to be more concentrated than the Stonepine Funds. Stonepine seeks to achieve their investment objective primarily by investing assets in publicly traded healthcare companies. Stonepine's investment focus is companies with commercial stage products generating sustainable revenue and companies with substantial financial assets (such as cash and royalty income streams).

Perkins Capital Management seeks to generate a positive real rate of return over an extended period of years for their clients. Investment strategies vary based on the type of account and the client's investment objectives, as well as the style of the individual portfolio manager. the firm's two main account types are equity and balanced.Perkins' approach to equity investing can be characterized as a search for opportunity. Their primary focus is on companies which appear to be undergoing positive change that may not be recognized in the market place. Such changes include new products, processes, strategies or management. They also search for companies that are likely candidates for acquisition by another company. Situations like this could provide higher earnings, and when acknowledged by others in the market place, could result in a higher price earnings ratio. Generally, equity investments will be held for a longer period of time in individual (taxable) accounts than they will be held in a pension or IRA (tax deferred) account. This provides the client with potentially lower capital gains on their taxable accounts.Perkins' fixed income investment approach seeks maximum income consistent with high quality investments. In their balanced accounts, the firm analyzes the outlook for both short-term and long-term interest rates. Perkins assesses both the domestic and international economic scene. In their opinion, the most important factors when selecting fixed income securities are the credit rating, yield curve analysis and liquidity. Perkins prefers a minimum credit rating of A by Moody's or Standard & Poor's rating service. They analyze the yield curves of government, corporate, and municipal bonds looking for inequities in yields which may provide an opportunity. Assessing liquidity requires that the security have excellent marketability.

Stonepine Capital Management focuses primarily, but not exclusively, on equity and equity-related securities in US publicly healthcare companies. The firm seeks to invest in companies whose valuations reflect a material discount to their fundamental value in the healthcare space. Stonepine typically prefers to invest in companies at a price reflecting a discount to current commercial and financial assets alone.The Stonepine Funds' investment objective is to achieve superior absolute returns while preserving capital. They have formed Special Purpose Vehicles (SPVs) whose investment objective may differ because these investments tend to be more concentrated than the Stonepine Funds. Stonepine seeks to achieve their investment objective primarily by investing assets in publicly traded healthcare companies. Stonepine's investment focus is companies with commercial stage products generating sustainable revenue and companies with substantial financial assets (such as cash and royalty income streams).

William E. Snee Chair at Memorial Sloan-Kettering Cancer Center

Equity Dynamics focuses on early-stage venture capital investments in technology, medical and healthcare companies located in the US. The firm will participate as a lead investor but this is not a requirement. They will also participate in investments with other venture capital firms.

MediGen Group provides seed and early-stage capital to new life sciences companies. The firm may fund proof-of-concept experiments and deal conceptualization. Companies should have large growing markets and strong intellectual property. They should also have defined regulatory paths to accelerate product development and mitigate FDA approval risk. MediGen seeks investments in companies with a clear path to monetization with substantial short-term value-creating milestones that allow for multiple exit opportunities and hedges against developmental setbacks