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TriSalus Life Sciences' Pressure-Enabled Drug Delivery (PEDD) Increases Penetration and Antitumor Activity of Anti-CEA CAR-T in Mouse Model of Liver Metastases

May 11, 2019 - Business Wire

A preclinical trial to be presented at the annual meeting of the American Association of Immunologists (AAI) demonstrated that administering anti-carcinoembryonic antigen (anti-CEA) CAR-T to liver metastases using high delivery pressure in an animal model simulating TriSalus(TM) Life Sciences ' innovative Pressure-Enabled Drug Delivery(TM) (PEDD(TM)) significantly increased penetration and antitumor activity when compared with standard low-pressure (LP) delivery.

PEDD delivery of CAR-T: In...