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How a parasitic fish inspired a new way to get drugs into the brain

May 16, 2019 - FierceBiotech

The blood-brain barrier normally blocks many types of drugsfrom entering the central nervous system, making it hard to treat brain disorders. Scientists from the University of Wisconsin-Madison and the University of Texas at Austin hope to solve that problem with the help of an unlikely ally: the jawless sea lamprey. And they have promising early evidence that a molecule derived from the creature could be used to ferry drugs directly to previously difficult-to-access diseased sites in the brain.

When the researchers combined the drug-delivery system they developed with an anti-cancer drug, they observedbetter treatment results in mice with brain tumors, according to a study published in the journal Science Advances. The team believes the findings offer hope for treating other brain dis...