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-Director/PDMR Shareholding

Shire plc (LSE: SHP, NASDAQ: SHPG) Notification of transaction by person discharging managerial responsibilities and person closely associated with them

1. Details of the person discharging managerial responsibilities ('PDMR') / person closely associated them ('PCA') a) Name Albert Stroucken / Gerda Stroucken 2. Reason for the notification a) Position / status Non-Executive Director (PDMR) / PCA of Albert Stroucken b) Initial notification / amendment Initial notification 3. Details of the

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